12.07.2023

FGCL-3019-093 LELANTOS ONE

A Phase 3, Randomized, Double-Blind, Trial of Pamrevlumab (FG-3019) or Placebo in Combination with Systemic Corticosteroids in Subjects with Non ambulatory Duchenne Muscular Dystrophy (DMD)

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12.07.2023

SPIMM-301

A Phase 3 Randomized, Double-Blind, Parallel-Group, PlaceboControlled Trial to Evaluate the Efficacy and Safety of Daily Subcutaneous Injections of Elamipretide in Subjects with Primary Mitochondrial Myopathy Followed by an Open-Label Treatment Extension

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12.07.2023

REN001-201

A DOUBLE-BLIND, PLACEBO-CONTROLLED, study to EVALUATE the EFFICACY and safety of 24 weeks treatment with REN001 in patients with primary mitochondrial myopathy (PMM)

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12.07.2023

PTC743-NEU-003-FA MOVE-FA

A randomized, parallel-arm, double-blind, placebo-controlled study with open-label extension to assess the efficacy and safety of Vatiquinone for the treatment of Friedreich Ataxia (move-fa)

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12.07.2023

PTC743-MIT-001-EP MIT-E

Efficacy and safety study of vatiquinone for the treatment of mitochondrial disease subjects with refractory epilepsy (MIT-E)

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12.07.2023

232SM201 NURTURE

An Open-Label Study to Assess the Efficacy, Safety, Tolerability, and Pharmacokinetics of Multiple Doses of ISIS 396443 Delivered Intrathecally to Subjects With Genetically Diagnosed and Presymptomatic Spinal Muscular Atrophy

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12.07.2023

OPBGC&RS 2011-004_CA2012

Prospective open label trial to evaluate the maintenance of the efficacy and the long term safety of EPI-743 in children with Leigh Disease

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12.07.2023

ION373-CS1 IONIS

A Phase 1-3, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Intrathecally Administered ION373 in Patients with Alexander Disease

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12.07.2023

DSC/14/2357/51

Open label, long-term safety, tolerability, and efficacy study of GIVINOSTAT in all DMD patients who have been previously treated in one of the GIVINOSTAT studies

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